Practice Test


Q1) Co-repressor is a: Show Answer


Q2) Reverse transcription was discovered by: Show Answer


Q3) In the Operon concept, the regulator gene regulates chemical reactions in the cell by: Show Answer


Q4) Central dogma of cytogenetics is: Show Answer


Q5) In an E. coli according to Operon concept, an operator gene combines with: Show Answer


Q6) Exons and introns are parts of: Show Answer


Q7) Eukaryotes have: Show Answer


Q8) In Rous sarcoma virus: Show Answer


Q9) Presence of F factor in bacteria: Show Answer


Q10) The viral genes express by: Show Answer


Q11) Which of the following is not carcinogen? Show Answer


Q12) According to Operon concept, regulator gene form: Show Answer


Q13) Which virus has a double stranded RNA? Show Answer


Q14) In lysogenic cycle, the virus is: Show Answer


Q15) In bacteria, exchange of genetic material between two different cells is brought by the process of: Show Answer


Q16) Phage host represents: Show Answer


Q17) Regulated unit of genetic material is called: Show Answer


Q18) A retrovirus is: Show Answer


Q19) Bacteriophages are: Show Answer


Q20) Provirus differs from prophage with regard to: Show Answer


Q21) Which virus has a rod shaped structure? Show Answer


Q22) Tryptophan Operon is: Show Answer


Q23) Oncogenic viruses are harmful in: Show Answer


Q24) Which of the following viruses have been extensively used to fuse cells in tissue culture: Show Answer


Q25) Jumping genes is maize were discovered by: Show Answer


Q26) Thalessemia is an example of: Show Answer


Q27) Who found occurrence of sexuality in bacteria? Show Answer


Q28) Operon consists of following: Show Answer


Q29) Restriction enzymes are used in genetic engineering because: Show Answer


Q30) Wild type E.coli cells are growing in a normal medium with glucose. They are transferred to medium containing only lactose as the sugar. Which one of the following changes take place? Show Answer


Q31) An environmental agent that triggers transcription from an operon is a: Show Answer


Q32) The lac operon is an example of: Show Answer


Q33) In split genes, the coding sequences are called: Show Answer


Q34) In case of cyanobacteria: Show Answer


Q35) The sequence of structural genes of Lac operon is: Show Answer


Q36) Which virus has a single stranded DNA: Show Answer


Q37) In lytic cycle, the virus is: Show Answer


Q38) Resistance to antibiotics is a genetic trait that spreads naturally from one type of bacterium to: Show Answer


Q39) Reverse transcriptase is: Show Answer


Q40) Transduction in bacteria is mediated by: Show Answer


Q41) The nuclease enzymes which begins its attack from a free end of a polynucleotide: Show Answer


Q42) Normally, DNA molecule has A-T, G-C pairing. However these bases can exist in alternative, valency consistent status, owing to rearrangement called: Show Answer


Q43) When DNA is exchanged between two bacteria via cytoplasmic bridges, the process is called: Show Answer


Q44) When a bacteriophage, in its lytic phase carries some of the bacterium partially digested chromosome with it to another host cell, the process is called: Show Answer


Q45) In general, bacterial genes are regulated at the time of: Show Answer


Q46) The activity of a repressor depends on whether: Show Answer


Q47) In gene therapy, DNA is inserted in a cell to compensate for: Show Answer


Q48) A gene carried by recombinant DNA is cloned when: Show Answer


Q49) A piece of nucleic acid used to find a gene, by forming a hybrid with it, is called as: Show Answer


Q50) Which of these viruses has DNA that occurs in both linear form and circular form? Show Answer


Q51) Palindromic sequence are recognized by enzymes: Show Answer


Q52) Which of the following is a palindromic sequence of nucleotides? Show Answer


Q53) Which is not an oncogenic virus? Show Answer


Q54) Restriction enzymes are nucleases and: Show Answer


Q55) Which is must for genetic engineering? Show Answer


Q56) Restriction endonuclease enzymes (RE) also called microscissors are widely used in genetic engineering. They cleave up foreign DNA at specific sites. These enzymes are synthesized by: Show Answer


Q57) Restriction endonuclease are enzymes discovered by Arber and Mathani (1962) and obtained from bacteria only. They are used as microscissors in genetic engineering. They recognise specific sequence of bases at a particular site, usually 4-6 base pairs and: Show Answer


Q58) Sticky ends of DNA strand are: Show Answer


Q59) Eli Lilly and Co. is famous for: Show Answer


Q60) Chimera DNA is: Show Answer


Q61) Callus and cancer both are undifferentiated mass of cells formed by uncontrolled mitosis. They differ as: Show Answer


Q62) The experiments of Briggs and Kings clearly proved that: Show Answer


Q63) One important consequence of interference of gene expression by another gene may be: Show Answer


Q64) In the Tryptophan operon, Tryptophan acts as: Show Answer


Q65) Enzymes required at the time e.g., for respiration are called: Show Answer


Q66) Two scientists working in Pasteur Institute proposed a gene action model and got Nobel Prize in 1965. Names: Show Answer


Q67) Recent work in genetics being carried out in U.S.A. and Japan is on: Show Answer


Q68) Consider the situtation : Synthesis of protein is going on, an amino acid is added in the medium, synthesis is stopped, what is involved? Show Answer


Q69) The gene which increases the frequency of mutation in other genes is called: Show Answer


Q70) Term metaxenia denotes the effect of pollen on: Show Answer


Q71) There is no masking in expression of genes in Neurospora, because it: Show Answer


Q72) Human growth hormone is now produced in large quantities by recombinant DNA technology. The previous source of this hormone, for treating pituitary dwarf, was: Show Answer


Q73) How does gene expression occur in prokaryotes? Show Answer


Q74) The minimum length of cistron in base pairs which synthesizes a polypeptide of 50 amino acids is: Show Answer


Q75) In a codon wobbling is restricted to: Show Answer


Q76) A community of similar individuals living a circumscribed area at a given time and capable of interbreeding is called: Show Answer


Q77) House keeping/constituent genes are: Show Answer


Q78) A split gene is: Show Answer


Q79) Gene expression in eukaryotes at a time never exceeds: Show Answer


Q80) Retroviruses are implicated as a cause for cancer in humans because they: Show Answer


Q81) When lactose is present: Show Answer


Q82) Introns occurs in: Show Answer


Q83) Aflatoxin produces cancer of the liver by inducing: Show Answer


Q84) The number of nucleotide present in yeast alanyl-t-RNA are: Show Answer


Q85) Britten and Davidsons (1969) gene-battery model is: Show Answer


Q86) Nirenberg synthesized a mRNA containing 34 polyadenine (A-A-A-A-A-A) and found a polypeptide formed of 11 polylysine, this proved that genetic code for lysine was: Show Answer


Q87) The DNA sequence of Lac-gene shows a mutation where the middle base of a triplet code has been substituted. However, the gene does not show any mutation and expression normal. This may be due to: Show Answer


Q88) Redundant parts of DNA or a gene are called: Show Answer


Q89) According to 1991 figures, about how many human genes have been mapped? Show Answer


Q90) Eugenics, Euthenics and Euphenics are related with Human Genetics. Which is concerned with improvement of present human race by providing better living condition i.e., good nature and nurture? Show Answer


Q91) Lac, operon of E. coli contains in continuity: Show Answer


Q92) Bacterial resistance to antibiotic is a genetic trait carried in the bacterial: Show Answer


Q93) In a tryptophan operon model, formation of tryptophan is restricted by: Show Answer


Q94) How many types of the genes the Lac operon model includes: Show Answer


Q95) In a lac-operon model, the addition of lactose induces the synthesis of: Show Answer


Q96) A collection of clones (genetically similar cells/organisms) having recombinant DNA is called: Show Answer


Q97) Hybrids are often superior to either parents due to: Show Answer


Q98) Controversies about doubtful parentage can now be settled by employing: Show Answer


Q99) Dr. Hargobind Khorana has been awarded Nobels prize for research on: Show Answer


Q100) Barbara McClintock's work showed that in maize: Show Answer


Q101) Two strains of bacterial suspensions are separated from one another with the help of bacteria proof glass filters, which of the following process would not occur? Show Answer


Q102) Each codon present on m-RNA and anticodon present in t-RNA is composed of: Show Answer


Q103) Which of the following unit is unrelated to DNA or gene? Show Answer


Q104) Recently the application of genetics in biotechnology and industry has become topic of discussion among different countires. This will become the part of: Show Answer


Q105) Galton is regarded as Father of Eugenics (science of being well born). Eugenic is concerned with: Show Answer


Q106) Dysgenic eugenics is to: Show Answer


Q107) The basis for DNA finger printing is: Show Answer


Q108) The Nobel prize of physiology and medicine in 1989 was awarded to: Show Answer


Q109) The recent techinque used for separating fragments of DNA is: Show Answer


Q110) Genes that are involved in turning on or off the transcription on a set of genes are called: Show Answer


Q111) Why is recombinant DNA technology called genetic engineering? Show Answer


Q112) Another popular name of recombinant technology is: Show Answer


Q113) Enzyme which acts like a scissor in genetic engineering is: Show Answer


Q114) A vector is used to carry foreign DNA in genetic engineering. Which one of the following is used as vector? Show Answer


Q115) The most novel vector having 2 sites for RE enzymes are: Show Answer


Q116) Restriction enzymes have been found in: Show Answer


Q117) Which one of the following pairs is correctly matched? Show Answer


Q118) A restriction enzymes breaks bonds between the: Show Answer


Q119) The sub branch of genetic engineering through which disorders are treated is called Gene Therapy. The father of biochemical disorder is: Show Answer


Q120) Concentration of inducible enzymes in the presence of their substrate may be increase: Show Answer


Q121) A poly-uridylic (Poly-U) chain of mRNA is called: Show Answer


Q122) The Eco-RI enzymes is obtained from: Show Answer


Q123) The DNA whose genes are to be transferred is multiplied through bacterial DNA (vectro or vehicle or carrier to DNA) in genetic engineering. This DNA is called: Show Answer


Q124) Cryptogram is: Show Answer


Q125) Ability to absorb foreign DNA is: Show Answer


Q126) The first artificial plant hybrid was made around 1717 by? Show Answer


Q127) Gene which is responsible for synthesis of polypeptide chain is called: Show Answer


Q128) An envelope surrounds the virus in: Show Answer


Q129) During lytic cycle, viral DNA is not affected by nucleases produced by it as: Show Answer


Q130) Restriction endonucleases ECO RI cleaves palindrome site of DNA duplex at: Show Answer


Q131) Which of the following organelles is associated with genetic engineering? Show Answer


Q132) Plants that receive the foreign genes through genetic engineering are called: Show Answer


Q133) A cell coded protein that is formed in response to infection with most animal viruses is called: Show Answer


Q134) Which of the following pairs is correctly matched? Show Answer


Q135) Viruses like herpes virus, Epstein-Barr virus, AIDS, HIV resemble each in being: Show Answer


Q136) AIDS is characterised by: Show Answer


Q137) Reverse transcription was frist shown by: Show Answer


Q138) Teminism was discovered in: Show Answer


Q139) First human interferon (antiviral protein) was produced by: Show Answer


Q140) First man made (genetically engineered) industrially important organism was Pseudomonas fluorecens called Super Bug. It was made by: Show Answer


Q141) Viral genome is changed to prorvirus/prophage state by: Show Answer


Q142) That nuclei control cell differentiation was proved in frog and toad by: Show Answer


Q143) A sequential expression of a set of human genes occurs, when a steroid molecule binds to the: Show Answer


Q144) During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle like structure. What is it's DNA binding sequence? Show Answer


Q145) What would happen if in a gene encoding a polypeptide of 50 amino acids will be (UAC) is mutated of UAA? Show Answer


Q146) How do the proto-oncogenes changed to oncogenes? Show Answer


Q147) How does a totipotent cell undergo differentiation? Show Answer


Q148) Which is the initial step in m-RNA maturation process? Show Answer


Q149) The central dogma of protein synthesis in teminism is: Show Answer


Q150) Molecular basis of organ differentiation depends on the modulation in transcription by: Show Answer


Q151) Which of the following correctly defines a transgenic animal: Show Answer


Q152) There are special proteins that help to open up DNA double helix infront of the replication fork. These proteins are: Show Answer


Q153) Who got the Nobel prize in medicine for their discovery of 'G-proteins' and the role of these proteins in the cells: Show Answer


Q154) Exonucleases cleaving nucleotides one at a time from the end of the polynucleotide chain are: Show Answer


Q155) Complete transduction is: Show Answer


Q156) Genetic engineering is possible because: Show Answer


Q157) Two bacteria found to be very useful in genetic engineering experiments are: Show Answer


Q158) At the time of organogenesis genes regulate the process at different levels and a different time due to: Show Answer


Q159) In Negative operon: Show Answer


Q160) Restriction enzymes: Show Answer


Q161) Process of introduction of foreign gene far improving genotype is called: Show Answer


Q162) Which one of the following makes use of RNA as a template to synthesize DNA? Show Answer


Q163) Which one of the following conditions though harmful in itself, is also a potential saviour from all mosquito borne infectious disease? Show Answer


Q164) In E. coli, during lactose metabolism repressor binds to: Show Answer


Q165) The genes are responsible for the growth and differentiation in living organisms through the regulation of: Show Answer


Q166) Which of the following is specifically used in genetic engineering? Show Answer


Q167) Restriction endonucleases: Show Answer


Q168) Cancer cells are more easily damaged by radiation than normal cells because they are: Show Answer


Q169) DNA finger printing refers to: Show Answer


Q170) What kind of evidence suggested that man is more closely related with chimpanzee than with other hominoid apes? Show Answer


Q171) In transgenics, expression of transgene in target tissue is determined by: Show Answer


Q172) The Ti plasmid, is often used for making transgenic plants. This plasmid is found in: Show Answer


Q173) The most likely reason for the development of resistance against pesticides in insect damaging a crop is: Show Answer


Q174) Supercoiled DNA can be traced in: Show Answer


Q175) Phosphorus is present in: Show Answer


Q176) In a given DNA segment ATG, ACC, AGG, ACC, CCA, ACA, the first base gets mutated. The effects of this on coding by this DNA segment will result in: Show Answer


Q177) Okazaki fragments are joined in a correct sequence by: Show Answer


Q178) In the lac operon, the structural genes are switched off when: Show Answer


Q179) In lac operon structural gene 'z' is responsible for the synthesis of the enzyme: Show Answer


Q180) When lactose is added to the culture of E. coli, a few of its molecules get into the cells with the help of: Show Answer


Q181) During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called? Show Answer


Q182) In the lac operon model, lactose molecules function a is: Show Answer


Q183) Protein synthesis in an animal cell occurs: Show Answer


Q184) E. coli cells with a mutated z gene of the lac operon cannot grow in medium containing only lactose as the source of energy because: Show Answer


Q185) Differentiation of organs and tissues in a developing organism, is associated with: Show Answer


Q186) Intron transcripts in heterogenous nuclear RNA (hn-RNA) are removed and exon transcripts are joined together under the direction of protein complexes. These complexes are: Show Answer


Q187) In regulation of gene expression in prokarytoes:
(a) Lactose acts as the suppressor for gene expression
(b) Tryptophan acts as the inducer for gene expression
(c) Regulator gene is the one that produces the repressor molecule Show Answer


Q188) Tumour causing viruses carry which of the proto-oncogene? Show Answer


Q189) Which of the following acts as genetic material in retro viruses? Show Answer


Q190) The term genome is used for: Show Answer


Q191) Synonymous codons are: Show Answer


Q192) Select correct one: Show Answer


Q193) Regulation of gene activity is carried out by: Show Answer


Q194) In Tryptophan operon, a repressor consists of co-repressor and apo-repressor. These two consist of: Show Answer


Q195) In lac operon model, the correct sequence of genes is: Show Answer


Q196) Prophage is formed by integration of E. coli DNA with: Show Answer


Q197) The phenomenon by which the phage DNA exists as part of the host DNA is called: Show Answer


Q198) The collection of cloned DNA segments obtained from complete genome is called: Show Answer


Q199) In operon model, regulator gene functions as: Show Answer


Q200) Genes involved in turning on and off of structural genes are: Show Answer


Q201) Lac operon is related to: Show Answer


Q202) According to the operon concept, the regulator gene regulates chemical reactions in the cell by: Show Answer


Q203) The modern concept of gene is that it is: Show Answer


Q204) SV 40 has five genes but the type of proteins synthesised by it is more than twice the number of genes present in it. It shows the presence of: Show Answer


Q205) Identify the true statements -
I. Pullorum disease of poultry is caused by virus.
II. Drones are produced by parthenogenesis.
III. Heterosis or hybrid vigour is the phenotypic superiority of the hybrid over either of its parents in one or more traits.
IV. A clone contains and expresses genetically engineered gene known as transgene.
V. Cross breeding is practised to develop homozygous pureline. Show Answer