Practice Test

Q1) The genetic material in most plant viruses is Show Answer

Q2) RNA is Show Answer

Q3) The hereditary material in tobacco mosaic virus is a Show Answer

Q4) The hereditary material in tobacco mosaic virus was discovered by Show Answer

Q5) Transfer RNA is synthesized: Show Answer

Q6) DNA is believed to be the genetic material because: Show Answer

Q7) If replication were conservative, which of the following banding patterns would Meselson and Stahl have found in the fourth generation? (Note: concentration refers to concentration of DNA). Show Answer

Q8) If a cell is treated with nucleic acid destructing material, which will firstly be prevented? Show Answer

Q9) The experimental system used in the studies on the discovery of replication of DNA has been: Show Answer

Q10) X-Ray diffraction technique was used by Wilkins and Franklin to ascertain structure of: Show Answer

Q11) The functional genetic unit is: Show Answer

Q12) The base sequence for a nucleic acid segment is given as GAG, AGG, GGA, CCA. From this it can be concluded that it is a segment of a: Show Answer

Q13) DNA polymerase is required for the synthesis of: Show Answer

Q14) Amino acid is carried by RNA at its: Show Answer

Q15) In yeast alanyl-tRNA, the number of nucleotides are: Show Answer

Q16) At 3' end t-RNA involved in transfer of amino acids: Show Answer

Q17) Replication of DNA in eukaryotes commences from: Show Answer

Q18) Heredity is brought about by transference from one generation to another of a substance with definite chemical having specific molecular constitution was mentioned by: Show Answer

Q19) Okazaki segments are: Show Answer

Q20) Which of the following is called adapter molecule? Show Answer

Q21) DNA replication is aided by: Show Answer

Q22) The element required for the activation of DNA and DNA polymerase is: Show Answer

Q23) For studying the metabolism of DNA radioautographic technique is used involving: Show Answer

Q24) Technique for detecting and screening the nutritional mutant in Neurospora crassa was developed by: Show Answer

Q25) A DNA molecule in which both strands have radioactive thymine is allowed to duplicate in an environment containing non-radioactive thymine. What will be the correct number of DNA molecules that contain same radio-active thymine after three duplications? Show Answer

Q26) What is the name of Noble laureates in relation with DNA? Show Answer

Q27) The transformation experiment conducted by Avery, MacLeod and McCarthy using Diplococcus bacteria proved that: Show Answer

Q28) The semi-conservative mode of DNA replication was proved by: Show Answer

Q29) Various metabolic activities of the cell are controlled and directed by: Show Answer

Q30) The RNA transporting amino acid to the protein synthesizing site is called: Show Answer

Q31) mRNA in prokaryotes is: Show Answer

Q32) The bits of DNA formed join with each other by an enzyme: Show Answer

Q33) Catalytic property of RNA was discovered by: Show Answer

Q34) The two strands of DNA are: Show Answer

Q35) The diameter of DNA molecule is: Show Answer

Q36) The approximate life span of m-RNA is: Show Answer

Q37) A protion of DNA has ACT, CAT, TCA, what would be the sequence of complementary DNA? Show Answer

Q38) The term heterochromatin was given by: Show Answer

Q39) Histones occupy the major grooves of DNA at an angle of: Show Answer

Q40) There are special protein that help to open up DNA double helix in front of replication fork. These proteins are: Show Answer

Q41) The transfer of genetic material from one cell to another by a phage is called: Show Answer

Q42) Autocatalytic function is shown by: Show Answer

Q43) In which of the following places, messenger RNA is found in a living cell? Show Answer

Q44) Functional unit of DNA which specifies the formation of a single peptide is: Show Answer

Q45) A mutant DNA is caused by insertion of extra base to DNA by a mutagen: Show Answer

Q46) Which of the following is not correct for DNA chain? Show Answer

Q47) Two strands of DNA are coiled around: Show Answer

Q48) Satellite DNA is present in: Show Answer

Q49) Plasmids are: Show Answer

Q50) Anticodon is present on: Show Answer

Q51) The instructions for the synthesis of a protein coat in a cell are always inscribed in the form of a: Show Answer

Q52) The double helix makes a complete turn: Show Answer

Q53) Which one of the following pair is correctly matched? Show Answer

Q54) Which one of the following units is unrelated to DNA or gene? Show Answer

Q55) A gene may best be defined according to its: Show Answer

Q56) Khorana synthesized a biologically functional tyrosine suppressor t-RNA of E. coli in 1979 it contained: Show Answer

Q57) The enzyme needed for repairing DNA break and releasing tension caused by rotation of DNA molecule is: Show Answer

Q58) When pure DNA was digested by nuclease, DNA fragments of all sizes were obtained. But when chromatin was digested with same enzyme, DNA fragmets of sizes, multiples of a smallest unit size were obtained. This suggests that in the chromatin, histone proteins are associated with DNA all along its length: Show Answer

Q59) Gene controls: Show Answer

Q60) Okazaki fragments are seen on: Show Answer

Q61) RNA primer is formed over: Show Answer

Q62) Who followed the trail of Griffith's work and proved DNA is the genetic material? Show Answer

Q63) Which object did Hershey and Chase (1952) choose to confirm that DNA is the hereditary material? Show Answer

Q64) Who was not awarded Nobel Prize alongwith Watson, Crick and Wilkins for an extensive work on the structure of DNA? Show Answer

Q65) The function of helix-destabilizing proteins is to: Show Answer

Q66) Why a protein cannot be a genetic material? Show Answer

Q67) The helical model for DNA given by Watson and Crick was: Show Answer

Q68) In function of 'DNA polymerase' is to help in the conversion: Show Answer

Q69) Genes in the intervening non-functional DNA segments are called: Show Answer

Q70) Which of the following is correct? Show Answer

Q71) Genes are made up of: Show Answer

Q72) Hargobind Khorana is credited for the synthesis of: Show Answer

Q73) To mobile DNA elements which move into the genome through RNA copies are called: Show Answer

Q74) Defective copies of functional genes are called: Show Answer

Q75) The structural stability of the double helix of DNA is ascribed largely to: Show Answer

Q76) Which of the RNA is smallest and used in feeding of amino acid to a ribosome? Show Answer

Q77) Formation of new DNA strand during replication occurs in: Show Answer

Q78) Which of the following can break and reseal DNA strand during replication? Show Answer

Q79) Replication of DNA is: Show Answer

Q80) When in a DNA, A-T becomes T-A and G-C becomes C-G, the pehnomenon is called: Show Answer

Q81) DNA segments (genes) have been found to move out of choroplasts and go into mitochondria. These have been termed as: Show Answer

Q82) DNA replication is: Show Answer

Q83) In 'Z' DNA pitch of each turn of helix is: Show Answer

Q84) The biochemical nature of gene (DNA) was shown by: Show Answer

Q85) 'Z' DNA shows: Show Answer

Q86) Approach of Meselson and Stahl to establish the semi-conservative replication of DNA was to use: Show Answer

Q87) Addition of sugar residue to proteins termed glycosylation occurs in: Show Answer

Q88) Enzymes involved in an unwinding of DNA at replication are: Show Answer

Q89) tRNA attaches amino acid at its: Show Answer

Q90) Which one of the following chemical characterisitics is not common to all living beings? Show Answer

Q91) The messenger RNA is termed as a working copy of the exact information contained in a segment of DNA strand. The process is called: Show Answer

Q92) The genes which continuously change their position on a chormosome are called: Show Answer

Q93) Certain genes do not generate functional m-RNA for any protein. Such genes are termed: Show Answer

Q94) RNA directed DNA polymerase is: Show Answer

Q95) When mRNA is synthesised on DNA the unwanted DNA regions are removed and regions coding for amino acids are joined together. This process is referred to as: Show Answer

Q96) Pyrimidine dimers in DNA are formed when the cells are exposed to: Show Answer

Q97) DNA elements which can switch their position are called: Show Answer

Q98) Who among the following established that RNA is the genetic material? Show Answer

Q99) On Laggin strand, new DNA is synthesized in short segments, called: Show Answer

Q100) Resistance to antibiotics is a genetic process that spreads naturally from one type of bacterium to: Show Answer

Q101) In vitro synthesis of polyribonucleotides and RNA was made by: Show Answer

Q102) The scientist who first synthesised DNA in vitro was: Show Answer

Q103) Artificial synthesis of DNA was done by: Show Answer

Q104) The best method to improve genetic quality of mankind is: Show Answer

Q105) RNA synthesis is continued by RNA-polymerase and: Show Answer

Q106) Genes which are active all the time synthesising substance needed by the cell are called? Show Answer

Q107) Which statement is wrong about DNA? Show Answer

Q108) If the bases sequence of one strand of DNA is GAT, TAG, CAT, GAC, what shall the sequence on its complementary strand? Show Answer

Q109) Ligase enzyme is used for: Show Answer

Q110) Okazaki fragments are seen during: Show Answer

Q111) Nuclease enzyme cause fragmentation of DNA at sites not protected by proteins. When pure DNA was digested with a nuclease, DNA fragments of all sizes were obtained but when chromatin was similarly digested DNA fragments of sizes that were obtained. This suggested that in the chromatin the histone proteins are associated with DNA all along its length: Show Answer

Q112) During the replication of DNA the two daughter molecules are obtained in the following manner: Show Answer

Q113) DNA contains the bases: Show Answer

Q114) For structure of nucleic acid, which of the following statements is wrong: Show Answer

Q115) There are several proteins that help to open up DNA double helix in front of the replication fork. These belong to the category of: Show Answer

Q116) Amino acids are transferred from cytoplasm to site of protein synthesis by: Show Answer

Q117) ATP is not spent during: Show Answer

Q118) Nature of DNA replication is: Show Answer

Q119) The maximum concentration of RNA is found in: Show Answer

Q120) An anticodon is a complementary to the nucleotide triplet in: Show Answer

Q121) In bacterial chromosomes, the nucleic acid polymers are: Show Answer

Q122) DNA synthesis can be specifically measured by estimating the incorpotation of radio labelled: Show Answer

Q123) The RNA that picks up specific amino acids from the amino acid pool in the cytoplasm to ribosome during protein synthesis is called: Show Answer

Q124) If a completely radioactive double stranded DNA molecule undergoes two rounds of replication in a non-radioactive medium, what will be radioactive status of the four resulting molecules? Show Answer

Q125) The chemical knives of DNA are: Show Answer

Q126) Radioactive thymidine when added to the medium surrounding living mammalian cells gets incorporated into the newly synthesized DNA. Which of the following types of chromatin is expected to become radioactive if cells are exposed to radioactive thymidine as soon as they enter the S phase? Show Answer

Q127) Human immuno deficiency virus (HIV) has a protein coat and a genetic material which is: Show Answer

Q128) Which is true of DNA helicases? Show Answer

Q129) Mechanism of DNA duplication is mainly: Show Answer

Q130) E. coli about to replicate was placed in a medium containing radioactive thymidine for five minutes. Then it was made to replicate in a normal medium. Which of following observation shall be correct? Show Answer

Q131) m-RNA is synthesised on DNA in template in which direction: Show Answer

Q132) Gene and cistron words are sometimes used synonymously because: Show Answer

Q133) HIV has a protein coat and a genetic material which is: Show Answer

Q134) Largest bacterial plasmid has Kilobases: Show Answer

Q135) Cauliflower mosaic virus has: Show Answer

Q136) DNA polymerase that helps in DNA replication is of: Show Answer

Q137) The total number of nitrogenous bases in human genome is estimated to be about: Show Answer

Q138) Which of the following pairs is correctly matched with regard to the codon and the amino acid coded by it? Show Answer

Q139) DNA repairing is done by: Show Answer

Q140) During replication of a bacterial chromosome, DNA synthesis starts from the replication origin site and: Show Answer

Q141) Find the correct match: Show Answer

Q142) Production of a human protein in bacteria by genetic engineering is possible because: Show Answer

Q143) Which one of the following makes use of RNA as a template to synthesize DNA? Show Answer

Q144) One gene-one enzyme hypothesis was posulated by: Show Answer

Q145) The Okazaki fragments in DNA chain growth: Show Answer

Q146) The length of DNA molecule greatly exceeds the dimensions of the nucleus in eukaryotic cells. How is this DNA accommondated? Show Answer

Q147) One gene-one enzyme relationship was established for the first time in: Show Answer

Q148) Telomere repetitive DNA sequences control the function of eukaryote chromosomes because they: Show Answer

Q149) The two polynucleotide chains in DNA are: Show Answer

Q150) Choose the wrong statement: Show Answer

Q151) In the DNA molecule: Show Answer

Q152) Which one of the following pairs of codons is correctly matched with their function or the single for the particular amino acid: Show Answer

Q153) Which one of the following also acts as a catalyst in a bacterial cell? Show Answer

Q154) Which of the nucleotide composition will be possible if DNA is double stranded? Show Answer

Q155) Which of the following is incorrect? Show Answer

Q156) In case of F. Griffith experiment on Streptococcus pneumoniae, which of the following is not able to cause pneumonia: Show Answer

Q157) Which of the following photographed x-ray diffraction pictures of crystalline DNA? Show Answer

Q158) The right handed DNA can acquire a left handed structure at least over a short distance. It will: Show Answer

Q159) Three types of DNA can be differentiated on the basis of their: Show Answer

Q160) The DNA replication in most bacteria starts at a single point, origin and moves: Show Answer

Q161) What is the composition of larger subunit of prokaryotic ribosome? Show Answer

Q162) Overlapping genes: Show Answer

Q163) Which statement is incorrect? Show Answer

Q164) Virus genome replicates in: Show Answer

Q165) For replication viruses use: Show Answer

Q166) The activity of nuclease does not affect phage DNA because it has: Show Answer

Q167) Match the list I and II and select the answering using the code given below the list:
1. Friedrick Griffith : Phenomenon of transformation
2. Gamow : A sequence of 3 nucleotide codes for a single amino acid
3. F. Miescher : Isolated DNA for the first time Show Answer

Q168) Match the list I and II and select the correct answer using the code given below in the list:
1. Ligase : Joins short segments of DNA together
2. DNA polymerase : Cuts DNA at specific DNA sequence
3. Helicase : Breaks the hydrogen bonds between complementary pairs during DNA replication
Show Answer

Q169) What makes the exact copying of DNA molecules possible? Show Answer

Q170) Satellite DNA is important because it Show Answer

Q171) Frederick Griffith conducted experiments testing the virulence of two strains of Streptococcus (R - strain and S-strain). His experiment has 4 specific 'treatments' to it.
Treatment 1, he injected mice with the R-strain and the mice lived.
Treatment 2, he injected mice with the S-strain and the mice died.
Treatment 3, he injected mice with heat-killed S-strain and the mice lived.
Treatment 4, he injected mice with heat-killed S-strain and the mice died.
Which treatment in his experiment is considered a control treatment? Show Answer

Q172) Frederick Griffith conducted experiments testing the virulence of two strains of Streptococcus (R - strain and S-strain). His experiment has 4 specific 'treatments' to it.
Treatment 1, he injected mice with the R-strain and the mice lived.
Treatment 2, he injected mice with the S-strain and the mice died.
Treatment 3, he injected mice with heat-killed S-strain and the mice lived.
Treatment 4, he injected mice with heat-killed S-strain mixed with R-strain and the mice died.
Which treatment in his experiment is considered the experimental treatment? Show Answer

Q173) Which of the following statements is correct?
I. The biochemical nature of genetic material was not defined from the experiments conducted by Griffith.
II. Working on transformation Avery et al concluded DNA is genetic material but not all biologists were convinced.
III. RNA is the genetic material in TMV, QB bacteriophage etc.
IV. DNA is the predominant genetic material while RNA performs dynamic functions of messenger and adapter.
V. Viruses having DNA genome and having shorter life span and evolve faster. Show Answer

Q174) The Okazaki fragments in DNA chain growth Show Answer

Q175) The length of DNA molecule greatly exceeds the dimensions of the nucleus in the eukaryotic cells. How is this DNA accomodated? Show Answer

Q176) The basis of life is Show Answer

Q177) Single stranded DNA is found in Show Answer

Q178) The enzyme DNA polymerase was discovered by Show Answer

Q179) DNA multiplication is called Show Answer

Q180) Okazaki fragments are produced during the synthesis of Show Answer

Q181) During the replication of DNA, the synthesis of DNA on lagging strand takes place in segments. These
segments are called Show Answer

Q182) In his bacteriophage experiments, Hershey and Chase demonstrated that DNA is genetic material in Show Answer

Q183) Okazaki fragments are joined in a correct sequence by Show Answer

Q184) Which enzyme joins DNA fragments? Show Answer

Q185) Statements
I. The four nucleotide bases are not necessarily present in DNA in exact equal
proportions.
II. The total amount of purines are equal to the total amount of pyrimidines.
III. DNA ligase enzyme act to hydrolyse or breakdown a polynucleotide chain into
its component nucleotides.
IV. Nuclease enzymes are capable of restoring an intact DNA duplex.
Of the above statements Show Answer

Q186) There are special proteins that help to open up DNA double helix in front of the replication fork. These
protein are Show Answer

Q187) Meselson and Stahl experiment proved Show Answer

Q188) Which of the following enzyme is used in DNA multiplication? Show Answer

Q189) The enzyme which helps to cut one strand of DNA duplex to release tension of coiling of two strands is Show Answer

Q190) DNA strand which is formed continuously in 5’ → 3’ direction is called Show Answer

Q191) During replication of DNA, Okazaki fragments are formed in the direction of Show Answer

Q192) The enzyme used to join the DNA fragments is Show Answer

Q193) In prokaryotic cells, which enzyme erases primer and fill gaps in DNA Show Answer

Q194) The Okazaki fragments in DNA chain growth Show Answer

Q195) When DNA replication starts Show Answer

Q196) In vitro synthesis of RNA and DNA was carried out first by Show Answer

Q197) Semi conservative replication of DNA was first demonstrated in Show Answer

Q198) In prokaryotes, the process of replication is catalysed by the following enzymes. Identify which of the
enzymes is best coordinate with role Show Answer

Q199) Meselson and Stahl experiment on semi-conservative replication demonstrates Show Answer

Q200) DNA repairing is done by Show Answer

Q201) The RNA primer is used in Show Answer

Q202) The scientist who was awarded Nobel-Prize in 1959 for in vitro synthesis of polyribonucleotide? Show Answer

Q203) DNA can be formed by Show Answer

Q204) During replication of a bacterial chromosome, DNA synthesis starts from a replication origin site and Show Answer

Q205) DNA replication includes Show Answer

Q206) Histone octamer contains Show Answer

Q207) During Meselson and Stahl’s experiments, heavy DNA was distinguished from normal DNA by centrifugation in Show Answer

Q208) Answer briefly
I. Which colour glycogen gives on its reaction with iodine solution?
II. What is satellite DNA?
III. Name three components of a nucleotide molecule
Correct option will all answers is Show Answer